Recently, researchers have developed new robotic sensor technology that can diagnose women's reproductive health issues in real time. Developed by researchers at Imperial College London and the University of Hong Kong, the technology can be used to measure hormones that affect fertility, sexual development and menstruation faster and cheaper than existing methods.
The study, published in Nature Communications, was published in the Department of Chemistry at Imperial College London and the School of Biomedical Sciences at the University of Hong Kong. It was tested in patients at Hammersmith Hospital, part of the Imperial University Healthcare NHS Trust.
One-third of women in England suffer from serious reproductive health problems such as infertility and early menopause. Doctors typically diagnose these conditions by performing a blood test to measure the amount of luteinizing hormone (LH) in the sample. Current blood tests cannot easily measure the rise and fall of LH levels, which is essential for normal fertility - the so-called LH pulse pattern is associated with reproductive disorders. It is currently not feasible to measure the LH pulse pattern in a clinical setting because the doctor needs to take a blood sample from the patient every 10 minutes for at least 8 hours. Furthermore, the analysis of these samples is time consuming and expensive.
In the study, the researchers used a new type of biosensor associated with robotic systems, which they called the robotic APTamer-enabled electrochemical reader (RAPTER). By monitoring the patient's hormonal pattern in real time, it has the potential to alter the clinical care of patients with reproductive disorders. In this study, a prototype RAPTER device was used to measure LH in the blood of a patient collected every ten minutes to produce an immediate result.
The team believes it can pave the way for more personalized medicine. They hope to develop this technology to give clinicians a clearer understanding of LH beats and to propose more effective treatments based on individual needs.
Professor Waljit Dhillo, one of the leading authors of Imperial College London and a professor of endocrinology and metabolism at NIHR, said: “Reproductive health issues are common among women in the UK and around the world. Some of these diseases can be diagnosed very long. Lead to treatment delays. Reproductive health problems can also affect women's physical and mental health. Clearly there is a need for faster and better diagnosis of these diseases. Our technology will enable clinicians to diagnose hormones that affect reproductive health faster and more accurately. Beating, thus providing better and more targeted treatment for women.
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