10 Million Cars Detect Intestinal Diseases in 10 Minutes

"Please note that there was a collective food poisoning incident in a school in Huanggu District. Some students were infected with blood and suspected of enterohemorrhagic E. coli..." A special inspection vehicle galloped to the scene. After 10 minutes, the inspection report came out...

At present, it is hot in summer and various diarrheal diseases enter the epidemic season. On June 29, the Shenyang Municipal Center for Disease Control and Prevention organized the city's disease control system to respond to a simulated zipper exercise for prevention and control of intestinal infectious diseases. There were more than 200 emergency mobile teams in 15 city and district disease control centers, and 35 vehicles participated in the exercises. During the exercise, an investment in a million-dollar “emergency on-site inspection vehicle” attracted special attention.

Hypothetical target: "Hemorrhagic E. coli"

At 9:00 in the morning, in the Shenyang City CDC hospital, with the city health bureau emergency public health emergency command "urgent drill began now," the directive was issued, the city's health system acute disease emergency response kicked off kick start At the drill site, relevant personnel braved the scorching sun, quickly put on a full set of vacuum chemical protective clothing, put on goggles, rubber gloves, and began to enter the state of preparation. In response to an on-site question from the “examination examiner”, a disease control officer responded fluently: “In addition to reporting to the city’s CDC, we also isolated and observed close contacts and took preventive medication. Subsequently, we raised a yellow alert in the area where patients were admitted. Lines... Infectious diseases include cholera, hepatitis A, typhoid fever, dysentery, infectious diarrhea, enteritis, and hemorrhagic E. coli."

Exploration camp: Vehicle worth more than a million yuan

When the "emergency on-site inspection vehicle" again entered the city's disease control center, the reporter boarded the car for an experiential interview.

The space inside the cabin is the same as an ordinary ambulance, but the facilities are very different. A CDC officer armed with chemical protection suits and armed forces is operating in accordance with the procedure: he only enters the inspection room from a special channel and sits in front of a special instrument.

"This is a self-made nucleic acid extractor!" he told reporters, pointing another not far away, said: "It's called a fluorescent quantitative PCR instrument, right, here is a car vacuum safety cabinet "Speaking of this, he demonstrated it on the spot: Disinfect his hands first, then stretch into two pairs of rubber gloves that are set in a transparent glass cabinet. After that, put on a gloved hand and carry out the experimental operation with the pre-assembled sample tube.

“The safety cabinet is vacuum-sterile to ensure that the test is absolutely safe.” Director Dong Xue of the Center for Microbiology Inspection of the Municipal Center for Disease Control and Prevention said that the value of this vehicle is more than 200,000 yuan, and the number of instruments inside it is in the range of 560,000 yuan. Around, add up to more than one million yuan.

Secret: The fastest 10 minutes out of the test results

At present, this is the only on-site inspection vehicle in Northeast China. Once an outbreak occurs, it will show its ability in the shortest possible time.

"For example, once the outbreak of enterohemorrhagic E. coli occurs, we will start the "gold standard card." The fastest detection results can be presented in 10-15 minutes." Director Dong Xue said, in addition, the use of "molecular biological testing" Technology, results can be achieved within 2 hours; using the "medium detection" technology, the results can be produced for up to one week. She stressed that the "negative pressure glove safety cabinet" on the vehicle can ensure that all tests are within the controllable range and ensure that the inspectors and test vehicles are free of contamination.

Director Dong Xue told reporters that with this "special weapon", it played an important role in epidemiological surveys, prevention and control of epidemic areas, and personnel isolation. It marked a new stage in disease control work in Shenyang.

Attachment: emergency site detection vehicle configuration

The sample transport box is also equipped with a sample transport box for the completion of transportation work.

Appearance such as gloves, this equipment is a three-level biological safety cabinet, used to treat the sample kept sealed and prevent the sample from being contaminated.

Car refrigerators also have car refrigerators that are used to store samples.

Fully automated nucleic acid extractors for the detection of samples such as fully automated nucleic acid extractors, fluorescence quantitative PCR instruments, and microscopes are equipped with high-tech equipment for rapid inspection.

Fluorescent Quantitative PCR instrument Dong Xue introduced that this rapid test vehicle only performs qualitative and rapid detection of pathogens. Under normal circumstances, it takes only 5 to 7 days after the bacteria have been cultivated to perform further tests. This is an accurate method.